Prof. Chih-mao HUANG

EDUCATION

• Ph.D. in Psychology, 2012 University of Illinois at Urbana-Champaign, USA.
• M.S. in Neuroscience, 2005 National Yang Ming University, Taiwan
• B.S. Life Science, 2001 National Tsing Hua University, Taiwan

RESEARCH INTERESTS

Dr. Huang specializes in geroscience, with a dedicated focus on the cognitive functioning and mental health of older adults. His research addresses core topics such as brain and cognitive sciences, network neuroscience of human cognition, cognitive and social neuroscience of aging, and psychiatric disorders. He is particularly interested in understanding brain connectivity, brain plasticity, and multimodal neuroimaging techniques, including resting-state and task-related fMRI, Diffusion MRI, and EEG. His work emphasizes exploring cognitive reserve, neural dynamics, and the neural basis of aging, with applications to promoting healthy aging, mitigating age-related cognitive decline, and developing innovative interventions such as neurofeedback-based cognitive training using virtual reality.

RECENT PUBLICATIONS

Huang, H.W., Li, P.Y., Chen, M.C., Liu, C.L., Chang, Y.X., Lin, Q., Lin, C.M., Huang, C.M.*, Wu, S.C.* (2025). Classification of internet addiction using machine learning on electroencephalography synchronization and functional connectivity. Psychological Medicine, 55, e148. doi:10.1017/S0033291725001035.

Wang, S.M. Wen, H.J., Huang, F., Sun, C.W., Huang C.M.*, Wang S.L.* (2025). White matter microstructural integrity mediates associations between prenatal endocrine-disrupting chemicals exposure and intelligence in adolescents. Neuroimage: Clinical. 45, 103758. https://doi.org/https://doi.org/10.1016/j.nicl.2025.103758.

Guu, S.F., Chao, Y.P., Huang, F.Y., Jeng, Y.T., NG, H.Y., Hsu, C.F., Chuang, C.H., Huang, C.M.*, Wu, C.W.W.* (2023). Interoceptive awareness: MBSR training alters information processing of salience network. Frontiers in Behavioral Neuroscience. 17:1008086. doi: 10.3389/fnbeh.2023.1008086.

Gao, M, Wong, N.M.L., Lin, C.M., Huang, C.M., Liu, H.L., Toh, C.H., Wu, C.W.W., Tsai, Y. F., Lee, S.H., Lee, T.M.C. (2023). Multimodal brain connectome–based prediction of suicide risk in people with late-life depression. Nature Mental Health, 1, 100-113. https://doi.org/10.1038/s44220-022-00007-7.

Patil, A.U., Lin, C.M., Lee, S.H., Huang, H.W., Wu, S.C., Madathil, D., Huang, C.M.* (2023). Review of EEG-based neurofeedback as a therapeutic intervention to treat depression. Psychiatry Research: Neuroimaging, 329, 111591. https://doi.org/10.1016/j.pscychresns.2023.111591.

Chang, Y.K., Erickson, K.I., Aghjayan, S.L., Chen, F.T., Li, R.H., Shih, J.R., Chang, S.H., Huang, C.M.*, Chu, C.H.* (2022). The multi-domain exercise intervention for memory and brain function in late-middle-aged and older adults at risk for Alzheimer’s disease: A protocol for Western-Eastern Brain Fitness Integration Training (WE-BFit) trial. Frontiers in Aging Neuroscience. 14:929789. doi: 10.3389/fnagi.2022.929789.

Huang, H.W. & Huang, C.M.* (2022). Developing cross-cultural neuropsychology through the lens of cross-cultural cognitive neuroscience. In J. Evans (Eds.), Understanding Cross-Cultural Neuropsychology: Science, Testing and Challenges. London: Routledge. doi:10.4324/9781003051497-4.

Shih, H.C., Kuo, M.E., Wu, C.W., Chao, Y.P., Huang, H.W., Huang, C.M.* (2022). The neurobiological basis of love: A meta-analysis of human functional neuroimaging studies of maternal and passionate love. Brain Sciences. 12(7), 830. doi: 10.3390/brainsci12070830.

Patil, A.U., Madathil, D., Huang, C.M.* (2021). Age-related and individual variations in altered prefrontal and cerebellar connectivity associated with the tendency of developing internet addiction. Human Brain Mapping, 42(14), 4525-4537. doi: 10.1002/hbm.25562.

Patil, A.U., Ghate, S., Madathil, D., Tzeng, O.J.L., Huang, H.W., Huang, C.M.* (2021). Static and dynamic functional connectivity supports the configuration of brain networks associated with creative cognition. Scientific Reports, 11(1), 165. doi:10.1038/s41598-020-80293-2. 

Patil, A.U., Madathil, D., Huang, C.M.* (2021). Healthy aging alters the functional connectivity of creative cognition in the default mode network and cerebellar network. Frontiers in Aging Neuroscience, 13:607988. doi: 10.3389/fnagi.2021.607988.

Huang, H.W., Nascimben, M., Wang, Y.Y., Fong, D.Y., Tzeng, O.J.L., Huang, C.M.* (2021). Which digit is larger? Brain responses to number and size interactions in a numerical Stroop task. Psychophysiology, 58 (3): e13744. doi: 10.1111/psyp.13744.

Huang, C.M., Fan, Y.T., Lee, S.H., Liu, H.L., Lin, C.M., Lee, T.M.C. (2019). Cognitive reserve-mediated neural modulation of emotional control and regulation in people with late-life depression. Social Cognitive and Affective Neuroscience, 14(8):849-860. doi: 10.1093/scan/nsz054.

Huang, C.M., Huang, H.W. (2019). Aging, neurocognitive reserve, and the healthy brain. Psychology of Learning and Motivation. 71. 175-213. doi: 10.1016/bs.plm.2019.07.006.

Fan, Y.T., Fang, Y.W., Chen, Y.P., Leshikar, E.D., Lin, C.P., Tzeng, O.J.L., Huang, H.W., Huang, C.M.* (2019). Aging, cognition, and the brain: effects of age-related variation in white matter integrity on neuropsychological function. Aging and Mental Health, 23, 831-839. doi: 10.1080/13607863.2018.1455804.

RESEARCH LABORATORY

Cognitive, Social and Clinical Neuroscience of Aging Laboratory
https://cmhuanglab.weebly.com/

RESEARCH INTERNSHIP OPPORTUNITIES

Research internship opportunities in Dr. Huang’s lab are ideal for students and early-career researchers interested in Cognitive, Social, and Clinical Neuroscience of Aging. Interns have the chance to participate in cutting-edge projects involving neuroimaging data analysis (fMRI, EEG, DTI), neurofeedback training with virtual reality, cross-cultural cognitive neuroscience studies, and network modeling of brain connectivity. Please contact Dr. Huang via email.